Lapachol
Cat. No.：YN251733
CAS No. ：84-79-7
| 产品名称: | Lapachol |
| CAS No.: | 84-79-7 |
| Chemical Name: | 2-hydroxy-3-(3-methyl-2-buten-1-yl)-1,4-naphthalenedione |
| Synonyms: | Greenhartin,CI75490,Tecomin,黄钟花醌,Bethabarra wood |
| 分子量: | 242.27 |
| 分子式: | C₁₅H₁₄O₃ |
| SMILES: | O=C(C(CC=C(C)C)=C1O)C2=CC=CC=C2C1=O |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | Lapachol是一种萘醌，最早从Tabebuia avellanedae(紫葳科)中分离得到。Lapachol 具有抗脓肿，抗溃疡，抗真菌，抗癌，抗血毒，抗炎，抗疟疾，防腐，抗肿瘤，抗病毒，抗菌，抗真菌和杀虫活性。 |
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Mata-Santos, T., Pinto, N.F., Mata-Santos, H.A., et al.Anthelmintic activity of lapachol, β-lapachone and its derivatives against Toxocara canis larvaeRev. Inst. Med. Trop. Sao Paulo57(3),197-204(2015)
Xu, H., Chen, Q., Wang, H., et al.Inhibitory effects of lapachol on rat C6 glioma in vitro and in vivo by targeting DNA topoisomerase I and topoisomerase IIJ. Exp. Clin. Cancer Res.35(1),178(2016)
Strauch, M.A., Tomaz, M.A., Monteiro-Machado, M., et al.Lapachol and synthetic derivatives: In vitro and in vivo activities against Bothrops snake venomsPLoS One14(1),(2019)
Peres, R.S., Santos, G.B., Cecilio, N.T., et al.Lapachol, a compound targeting pyrimidine metabolism, ameliorates experimental autoimmune arthritisArthritis Res. Ther.19(1),47(2017)
de Almeida, E.R., da Silva Filho, A.A., do Santos, E.R., et al.Antiinflammatory action of lapacholJ. Ethnopharmacol.29(2),239-241(1990)
