Chloramphenicol succinate sodium
Cat. No.:YN251757
产品名称: | Chloramphenicol succinate sodium |
CAS No.: | 982-57-0 |
Chemical Name: | 1-[(2R,3R)-2-[(2,2-Dichloroacetyl)amino]-3-hydroxy-3-(4-nitrophenyl)propyl] Ester Butanedioic Acid Sodium Salt; Mono[(2R,3R)-2-[(dichloroacetyl)amino]-3-hydroxy-3-(4-nitrophenyl)propyl] Ester Butanedioic Acid Monosodium Salt; Betamicetin; Chloramphenicol |
Synonyms: | 氯霉素琥珀酸钠 |
分子量: | 445.18 |
分子式: | C₁₅H₁₅Cl₂N₂NaO₈ |
SMILES: | O=C(CCC(O[Na])=O)OC[C@H]([C@@H](C1=CC=C(C=C1)[N+]([O-])=O)O)NC(C(Cl)Cl)=O |
存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
运输: | Room temperature in continental US; may vary elsewhere. |
产品描述: | Chloramphenicol succinate sodium 是 Chloramphenicol 的前药,具有血液学毒性。Chloramphenicol succinate sodium 是琥珀酸脱氢酶 (SDH) 的竞争底物和抑制剂,可能是其产生毒性的原因。 |
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Bartz, et al.: J. Biol. Chem., et al.: 172, 445 (1948), Gottlieb, et al.: J. Bacteriol., 55, 409 (1948), Szulczewski, D., et al.: Anal. Profiles Drug Subs., 4, 47 (1975), Price, A., et al.: J. Antibiot., 43, 118 (1981), Shalit, I., et al.: Drugs, 28, 281 (1984),