Clindamycin hydrochloride monohydrate
Cat. No.：YN251760
| 产品名称: | Clindamycin hydrochloride monohydrate |
| CAS No.: | 58207-19-5 |
| Chemical Name: | (2S-trans)-methyl 7-chloro-6,7,8-trideoxy-6-[[(1-methyl-4-propyl-2-pyrrolidinyl)carbonyl]amino]-1-thio-L-threo-α-D-galacto-octopyranoside, monohydrochloride, monohydrate |
| Synonyms: | Clindamycin alcoholate |
| 分子量: | 479.46 |
| 分子式: | C₁₈H₃₆Cl₂N₂O₆S |
| SMILES: | CCC[C@H]1CN(C)[C@H](C(N[C@]([C@@]2([H])O[C@H](SC)[C@H](O)[C@@H](O)[C@H]2O)([H])[C@H](C)Cl)=O)C1.[H]Cl.[H]O[H] |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | Clindamycin hydrochloride monohydrate 是一种口服有效的蛋白质合成抑制剂，其具有以亚抑制浓度 (sub-MICs) 在金黄色葡萄球菌中毒力因子表达的能力。Clindamycin hydrochloride monohydrate 的抗性是由 50S 核糖体亚基 (23S rRNA) 中抗生素结合位点的酶促甲基化产生。Clindamycin hydrochloride monohydrate 能降低杀白细胞毒素 (PVL)、毒性休克-葡萄球菌毒素 (TSST-1) 或 α |
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Spížek, J., and Řezanka, T.Lincomycin, clindamycin and their applicationsAppl. Microbiol. Biotechnol.64(4),455-464(2004)
Dahl, E.L., and Rosenthal, P.J.Multiple antibiotics exert delayed effects against the Plasmodium falciparum apicoplastAntimicrob. Agents Chemother.51(10),3485-3490(2007)
Karlström, Å., Boyd, K.L., English, B.K., et al.Treatment with protein synthesis inhibitors improves outcomes of secondary bacterial pneumonia after influenzaJ. Infect. Dis.199(3),311-319(2009)
