Gramicidin A
Cat. No.：YN251862
| 产品名称: | Gramicidin A |
| CAS No.: | 11029-61-1 |
| Chemical Name: | (R)-2-((2S,5R,8S,11R,14S,17R,20S,26S)-2-((1H-indol-3-yl)methyl)-17-isobutyl-5,8,11,26-tetraisopropyl-14,20-dimethyl-4,7,10,13,16,19,22,27,28-nonaoxo-3,6,9,12,15,18,21,24,25-nonaazaoctacosanamido)-N-((5S,8R,11S,14R,17S)-5,11-bis((1H-indol-3-yl)methyl)-1-hy |
| Synonyms: | VGALAVVVWLWLWLWG |
| 分子量: | 1882.29 |
| 分子式: | C₉₉H₁₄₀N₂₀O₁₇ |
| SMILES: | C[C@H]([C@@](C[C@H]([C@@H]1C)OC(/C=C/C(O)=O)=O)(O[C@@H]1C(C)C)O)[C@H](O)[C@@H]([C@](OC(/C(OC)=C/C(C)=C/[C@H]2C)=O)([H])[C@H](/C=C/C=C(C[C@@H]([C@@H]2O)C)\C)OC)C |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | Gramicidin A is a peptide component of gramicidin, anantibioticmixture originally isolated from B. brevis. Gramicidin A is a highly hydrophobic channel-forming ionophore that forms channels in model membranes that are permeable to monovalent cations. Gram |
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Kelkar, D.A., and Chattopadhyay, A.The gramicidin ion channel: A model membrane proteinBiochim. Biophys. Acta1768(9),2011-2025(2007)
David, J.M., Owens, T.A., Inge, L.J., et al.Gramicidin A blocks tumor growth and angiogenesis through inhibition of hypoxia-inducible factor in renal cell carcinomaMol. Cancer Ther.13(4),788-799(2014)
