Tazobactam sodium
Cat. No.：YN251902
CAS No. ：89785-84-2
| 产品名称: | Tazobactam sodium |
| CAS No.: | 89785-84-2 |
| Chemical Name: | 4,4-dioxide 3-methyl-7-oxo-3-(1H-1,2,3-triazol-1-ylmethyl)-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid, monosodium salt |
| Synonyms: | Tazobactam acid Sodium, Tazobactamum Sodium |
| 分子量: | 322.27 |
| 分子式: | C₁₀H₁₁N₄NaO₅S |
| SMILES: | C[C@]([C@@H](N1[C@@]2([H])CC1=O)C(O[Na])=O)([S]2(=O)=O)CN3C=CN=N3 |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | Tazobactam sodium 是 β-内酰胺酶抑制剂类抗生素。Ceftolozane 与Tazobactam 联合应用，可提高头孢噻嗪对多种产 ESBL 肠杆菌科和部分类杆菌属的抗菌活性。 |
| IC50和靶点: | |
| In Vitro: | |
| In Vivo: | |
| Clinical Trial: | |
| Solvent & Solubility: |
Drawz, S.M., and Bonomo, R.A.Three decades of β-lactamase inhibitorsClin. Microbiol. Rev.23(1),160-201(2010)
Jones, R.N., Pfaller, M.A., Fuchs, P.C., et al.Piperacillin/tazobactam (YTR 830) combination. Comparative antimicrobial activity against 5889 recent aerobic clinical isolates and 60 Bacteroides fragilis group strainsDiagn. Microbiol. Infect. Dis.12(6),489-494(1989)
Craig, W.A., and Andes, D.R.In vivo activities of ceftolozane, a new cephalosporin, with and without tazobactam against Pseudomonas aeruginosa and Enterobacteriaceae, including strains with extended-spectrum β-lactamases, in the thighs of neutropenic miceAntimicrob. Agents Chemother.57(4),1577-1582(2013)
