Euphorbiasteroid
Cat. No.:YN420303
产品名称: | Euphorbiasteroid |
CAS No.: | 28649-59-4 |
Chemical Name: | benzeneacetic acid, (1aR,2'R,2E,4aR,6S,7S,7aR,8S,11aS)-4a,8-bis(acetyloxy)-1,1a,4,4a,5,6,7,7a,8,10,11,11a-dodecahydro-1,1,3,6-tetramethyl-4-oxospiro[9H-cyclopenta[a]cyclopropa[f]cycloundecene-9,2'-oxiran]-7-yl ester |
Synonyms: | 千金子甾醇 |
分子量: | 552.66 |
分子式: | C₃₂H₄₀O₈ |
SMILES: | CC(O[C@@](C[C@H](C)[C@@H]1OC(CC2=CC=CC=C2)=O)(C(/C(C)=C\[C@@H](C3(C)C)[C@@H]3CC[C@@]45CO5)=O)[C@@]1([H])[C@@H]4OC(C)=O)=O |
存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
运输: | Room temperature in continental US; may vary elsewhere. |
产品描述: | Euphorbiasteroid 是续随子中的三环二萜,可抑制 tyrosinase 活性,增强AMPK的磷酸化,具有抗癌、抗病毒、抗肥胖及多重耐药调节作用。 |
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Adolf, W., Hecker, E., Balmain, A., et al.“Euphorbiasteroid” (epoxy-lathyrol). A new tricyclic diterpene from Euphorbia lathyris L.Tetrahedron Lett.11(26),2241-2244(1970)
Park, S.-J., Park, J.H., Han, A., et al.Euphorbiasteroid, a component of Euphorbia lathyris L., inhibits adipogenesis of 3T3-L1 cells via activation of AMP-activated protein kinaseCell Biochem. Funct.33(4),220-225(2015)
Guo, F., Li, X., Zhang, C., et al.Roles and mechanisms of Fas/FasL in the apoptosis of HL-60 cells induced by euphorbiasteroidJ. Int. Oncology41(9),679-684(2014)
Choi, J.S., Kang, N.S., Min, Y.K., et al.Euphorbiasteroid reverses P-glycoprotein-mediated multi-drug resistance in human sarcoma cell line MES-SA/Dx5Phytother. Res.24(7),1042-1046(2010)