GZD856
Cat. No.：YN440033
CAS No. ：1257628-64-0
规格
价格(RMB)
库存
| 产品名称: | GZD856 |
| CAS No.: | 1257628-64-0 |
| Chemical Name: | |
| Synonyms: | |
| 分子量: | 532.56 |
| 分子式: | C₂₉H₂₇F₃N₆O |
| SMILES: | O=C(NC1=CC=C(CN2CCN(C)CC2)C(C(F)(F)F)=C1)C3=CC=C(C)C(C#CC4=CN5C(N=C4)=CC=N5)=C3 |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | GZD856是一种有效的，有口服活性的PDGFRα/β抑制剂，IC50分别为 68.6 和 136.6 nM。也是Bcr-AblT315I的抑制剂，对 Bcr-Abl 和 T315I 突变型的IC50分别为 19.9 和 15.4 nM。 具有抗肺癌活性。 |
| IC50和靶点: | [{name:"PDGFRα:68.6 nM (IC50)"},{name: "PDGFRβ:136.6 nM (IC50)"},{name: "Bcr-AblT315I:15.4 nM (IC50)"},{name: "Bcr-Abl:19.9 nM (IC50)"}] |
| In Vitro: | |
| In Vivo: | |
| Clinical Trial: | |
| Solvent & Solubility: |
