Imatinib D8
Cat. No.：YN440322
CAS No. ：1092942-82-9
规格
价格(RMB)
库存
| 产品名称: | Imatinib D8 |
| CAS No.: | 1092942-82-9 |
| Chemical Name: | 4-[(4-Methyl-1-piperazinyl-2,2,3,3,5,5,6,6-d8)methyl]-N-[4-methyl-3-[[4-(3-pyridinyl)-2-pyrimidinyl]amino]phenyl]benzamide; CGP 57148-d8; Genfatinib-d8 |
| Synonyms: | STI571 D8; CGP-57148B D8 |
| 分子量: | 501.65 |
| 分子式: | C₂₉H₂₃D₈N₇O |
| SMILES: | O=C(NC1=CC=C(C)C(NC2=NC=CC(C3=CC=CN=C3)=N2)=C1)C4=CC=C(CN5C([2H])([2H])C([2H])([2H])N(C)C([2H])([2H])C5([2H])[2H])C=C4 |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | Imatinib D8 (STI571 D8) 是 Imatinib (STI571) 的氘代物。Imatinib 是一种口服生物可用的酪氨酸激酶抑制剂，可选择性抑制 BCR/ABL，v-Abl，PDGFR，c-kit 激酶活性。 |
| IC50和靶点: | |
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| Solvent & Solubility: |
Schindler, T., et al.: Science, 289, 1938 (2000)
Drucker, B.J., et al.: N. Engl. J. Med., 344, 1031 (2001)
