GZD824 dimesylate
Cat. No.:YN440338
产品名称: | GZD824 dimesylate |
CAS No.: | 1421783-64-3 |
Chemical Name: | |
Synonyms: | HQP1351 dimesylate |
分子量: | 724.77 |
分子式: | C₃₁H₃₅F₃N₆O₇S₂ |
SMILES: | O=C(NC1=CC=C(CN2CCN(C)CC2)C(C(F)(F)F)=C1)C3=CC=C(C)C(C#CC4=CN=C(NN=C5)C5=C4)=C3.CS(=O)(O)=O.CS(=O)(O)=O |
存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
运输: | Room temperature in continental US; may vary elsewhere. |
产品描述: | GZD824 dimesylate (HQP1351 dimesylate) 是一种有口服活性的pan-Bcr-Abl抑制剂,除了抑制野生型 Bcr-Abl (IC50=0.34 nM) 之外,对突变型 Bcr-Abl 也具有广泛的抑制活性并且对野生型。GZD824 dimesylate 具有抗肿瘤作用。 |
IC50和靶点: | |
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In Vivo: | |
Clinical Trial: | |
Solvent & Solubility: |