Bafetinib
Cat. No.:YN440406
产品名称: | Bafetinib |
CAS No.: | 859212-16-1 |
Chemical Name: | N-[3-([4,5'-bipyrimidin]-2-ylamino)-4-methylphenyl]-4-[[(3S)-3-(dimethylamino)-1-pyrrolidinyl]methyl]-3-(trifluoromethyl)-benzamide |
Synonyms: | 巴氟替尼; INNO-406; NS-187 |
分子量: | 576.62 |
分子式: | C₃₀H₃₁F₃N₈O |
SMILES: | O=C(C1=CC=C(C(C(F)(F)F)=C1)CN2C[C@@H](N(C)C)CC2)NC3=CC=C(C)C(NC4=NC=CC(C5=CN=CN=C5)=N4)=C3 |
存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
运输: | Room temperature in continental US; may vary elsewhere. |
产品描述: | Bafetinib是具有抗肿瘤活性的Lyn/Bcr-Abl酪氨酸激酶抑制剂。 |
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Kimura, S., Naito, H., Segawa, H., et al.NS-187, a potent and selective dual Bcr-Abl/Lyn tyrosine kinase inhibitor, is a novel agent for imatinib-resistant leukemiaBlood106(12),3948-3954(2005)