Lanabecestat
Cat. No.：YN380011
CAS No. ：1383982-64-6
| 产品名称: | Lanabecestat |
| CAS No.: | 1383982-64-6 |
| Chemical Name: | (1α,1′R,4β)-4-methoxy-5′′-methyl-6′-[5-(1-propyn-1-yl)-3-pyridinyl]-dispiro[cyclohexane-1,2′-[2H]indene-1′(3′H),2′′-[2H]imidazol]-4′′-amine |
| Synonyms: | AZD3293; LY3314814 |
| 分子量: | 412.53 |
| 分子式: | C₂₆H₂₈N₄O |
| SMILES: | CC#CC1=CC(C2=CC([C@@]34N=C(C)C(N)=N4)=C(C[C@@]53CC[C@@H](OC)CC5)C=C2)=CN=C1 |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | Lanabecestat (AZD3293) 是一种具有口服活性的，可透过血脑屏障的BACE1抑制剂，Ki值为 0.4 nM。 |
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Eketjäll, S., Janson, J., Kaspersson, K., et al.AZD3293: A novel, orally active BACE1 inhibitor with high potency and permeability and markedly slow off-rate kineticsJ. Alzheimers Dis.50(4),1109-1123(2016)
