(1α,1'S,4β)-Lanabecestat
Cat. No.:YN380012
CAS No. :1384082-96-5
产品名称: | (1α,1'S,4β)-Lanabecestat |
CAS No.: | 1384082-96-5 |
Chemical Name: | |
Synonyms: | (1α,1'S,4β)-AZD3293; (1α,1'S,4β)-LY3314814 |
分子量: | 412.53 |
分子式: | C₂₆H₂₈N₄O |
SMILES: | NC(C(C)=N1)=N[C@]21C3=C(C=CC(C4=CC(C#CC)=CN=C4)=C3)C[C@]52CC[C@@H](OC)CC5 |
存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
运输: | Room temperature in continental US; may vary elsewhere. |
产品描述: | (1α,1'S,4β)-Lanabecestat ((1α,1'S,4β)-AZD3293) 是一种BACE1抑制剂,IC50分别为 2.2 nM (TR-FRET 测定) 和 0.28 nM (sAPPp释放测定),详细信息请参考专利文献 WO2012087237A1 中的化合物 20a。 |
IC50和靶点: | |
In Vitro: | |
In Vivo: | |
Clinical Trial: | |
Solvent & Solubility: |