Zanubrutinib
Cat. No.:YN440032
产品名称: | Zanubrutinib |
CAS No.: | 1691249-45-2 |
Chemical Name: | (7S)-4,5,6,7-tetrahydro-7-[1-(1-oxo-2-propen-1-yl)-4-piperidinyl]-2-(4-phenoxyphenyl)-pyrazolo[1,5-a]pyrimidine-3-carboxamide |
Synonyms: | 泽布替尼; BGB-3111 |
分子量: | 471.55 |
分子式: | C₂₇H₂₉N₅O₃ |
SMILES: | NC(C1=C2N(N=C1C3=CC=C(OC4=CC=CC=C4)C=C3)[C@H](C5CCN(C(C=C)=O)CC5)CCN2)=O |
存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
运输: | Room temperature in continental US; may vary elsewhere. |
产品描述: | Zanubrutinib (BGB-3111) 是一个选择性的Bruton tyrosine kinase(Btk) 抑制剂。 |
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Guo, Y., Liu, Y., Hu, N., et al.Discovery of zanubrutinib (BGB-3111), a novel, potent, and selective covalent inhibitor of bruton's tyrosine kinaseJ. Med. Chem.62(17),7923-7940(2019)