PRN1008
Cat. No.：YN440151
CAS No. ：1575596-29-0
规格
价格(RMB)
库存
| 产品名称: | PRN1008 |
| CAS No.: | 1575596-29-0 |
| Chemical Name: | |
| Synonyms: | PRN1008 |
| 分子量: | 665.76 |
| 分子式: | C₃₆H₄₀FN₉O₃ |
| SMILES: | NC1=C2C(C3=C(C=C(OC4=CC=CC=C4)C=C3)F)=NN([C@H]5CN(CCC5)C(/C(C#N)=C/C(C)(N6CCN(C7COC7)CC6)C)=O)C2=NC=N1 |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | PRN1008 是布鲁顿氏酪氨酸激酶(BTK)可逆的、选择性的、有口服活性的共价抑制剂，其IC50值为 1.3 nM。 |
| IC50和靶点: | [{name:"BTK:1.3 nM (IC50)"},{name: "BMX:1.0 nM (IC50)"},{name: "ITK:440 nM (IC50)"},{name: "TEC:0.8 nM (IC50)"},{name: "RLK:1.2 nM (IC50)"},{name: "BLK:6.3 nM (IC50)"},{name: "EGFR:520 nM (IC50)"},{name: "ERBB2:3900 nM (IC50)"},{name: "ERBB4:11.3 nM (IC50)"}] |
| In Vitro: | |
| In Vivo: | |
| Clinical Trial: | |
| Solvent & Solubility: |
