ARQ 531
Cat. No.:YN440152
产品名称: | ARQ 531 |
CAS No.: | 2095393-15-8 |
Chemical Name: | |
Synonyms: | ARQ 531;JTZ51LIXN4;(2-Chloro-4-phenoxyphenyl)(4-(((3R,6S)-6-(hydroxymethyl)tetrahydro-2H-pyran-3-yl)amino)-7h-pyrrolo[2,3-d]pyrimidin-5-yl)methanone;1,5-anhydro-2-{[5-(2-chloro-4-phenoxybenzene-1-carbonyl)-7H-pyrrolo[2,3-d]pyrimidin-4-yl]amino}-2,3,4-trid |
分子量: | 478.93 |
分子式: | C₂₅H₂₃ClN₄O₄ |
SMILES: | O=C(C1=C(C=C(OC2=CC=CC=C2)C=C1)Cl)C3=CNC4=NC=NC(N[C@@H]5CC[C@@H](CO)OC5)=C34 |
存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
运输: | Room temperature in continental US; may vary elsewhere. |
产品描述: | ARQ 531 是BTK可逆的、非共价的、具有口服活性的抑制剂,其对 WT-BTK 和 C481S-BTK 的IC50值分别为 0.85 nM 和 0.39 nM。 |
IC50和靶点: | |
In Vitro: | |
In Vivo: | |
Clinical Trial: | |
Solvent & Solubility: |