CG-806
Cat. No.：YN440158
CAS No. ：1370466-81-1
规格
价格(RMB)
库存
| 产品名称: | CG-806 |
| CAS No.: | 1370466-81-1 |
| Chemical Name: | 1-(3-Fluoro-4-(7-(4-methyl-1H-imidazol-2-yl)-1-oxoisoindolin-4-yl)phenyl)-3-(3-(trifluoromethyl)phenyl)urea; CG-806; CG-026806 |
| Synonyms: | 7W3FGR71NN;CG026806;1-(3-fluoro-4-(7-(4-methyl-1H-imidazol-2-yl)-1-oxoisoindolin-4-yl)phenyl)-3-(3-(trifluoromethyl)phenyl)urea;1-(3-Fluoro-4-(7-(5-methyl-1H-imidazol-2-yl)-1-oxo-2,3-dihydro-1H-isoindo-1-4-yl)-phenyl)-3-(3-trifluoromethyl-phenyl)urea;Urea |
| 分子量: | 509.45 |
| 分子式: | C₂₆H₁₉F₄N₅O₂ |
| SMILES: | O=C(NC1=CC=CC(C(F)(F)F)=C1)NC2=CC=C(C3=CC=C(C4=NC=C(C)N4)C5=C3CNC5=O)C(F)=C2 |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | CG-806 是一种口服，有效且非共价的泛-FLT3/泛-BTK抑制剂，对FLT3的IC50值为 0.08 µM。CG-806 对FLT3野生型转染的 Ba/F3 细胞的IC50值为 11 nM。 |
| IC50和靶点: | |
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| Solvent & Solubility: |
Hongying Z., et al.: EHA., 265993, 203(2019)
Hongying Z., et al. : Cancer Res., 79, 13(2019)
Hongying Z., et al.:Cancer Res., 78,13(2018)
