Spebrutinib
Cat. No.：YN440371
CAS No. ：1202757-89-8
规格
价格(RMB)
库存
| 产品名称: | Spebrutinib |
| CAS No.: | 1202757-89-8 |
| Chemical Name: | N-[3-[[5-fluoro-2-[[4-(2-methoxyethoxy)phenyl]amino]-4-pyrimidinyl]amino]phenyl]-2-propenamide |
| Synonyms: | AVL-292; CC-292 |
| 分子量: | 423.44 |
| 分子式: | C₂₂H₂₂FN₅O₃ |
| SMILES: | COCCOC1=CC=C(NC2=NC=C(F)C(NC3=CC=CC(NC(C=C)=O)=C3)=N2)C=C1 |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | Spebrutinib (AVL-292; CC-292) 是共价，高选择性和口服活性的Btk抑制剂，IC50为0.5 nM。 |
| IC50和靶点: | |
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| Clinical Trial: | |
| Solvent & Solubility: |
Evans, E.K., Tester, R., Aslanian, S., et al.Inhibition of Btk with CC-292 provides early pharmacodynamic assessment of activity in mice and humansJ. Pharmacol. Exp. Ther.346(2),219-228(2013)
