Ibrutinib deacryloylpiperidine
Cat. No.:YN440415
产品名称: | Ibrutinib deacryloylpiperidine |
CAS No.: | 330786-24-8 |
Chemical Name: | 3-(4-Phenoxyphenyl)-1H-pyrazolo(3,4 d)pyrimidin-4-amine |
Synonyms: | IBT4A |
分子量: | 303.32 |
分子式: | C₁₇H₁₃N₅O |
SMILES: | NC1=C2C(NN=C2C3=CC=C(OC4=CC=CC=C4)C=C3)=NC=N1 |
存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
运输: | Room temperature in continental US; may vary elsewhere. |
产品描述: | Ibrutinib deacryloylpiperidine (IBT4A) 是 Ibrutinib 的一种杂质。Ibrutinib 是一种不可逆的选择性 Btk 抑制剂,IC50为 0.5 nM。 |
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MacGlashan, D., et. al.: Int. Immunol., 11, 475 (2011)
Li, X., et al.: J. Med. Chem., 58, 9625 (2015)