CC-671
Cat. No.：YN290087
CAS No. ：1618658-88-0
| 产品名称: | CC-671 |
| CAS No.: | 1618658-88-0 |
| Chemical Name: | 4-[[4-(cyclopentyloxy)-5-(2-methyl-6-benzoxazolyl)-7H-pyrrolo[2,3-d]pyrimidin-2-yl]amino]-3-methoxy-N-methyl-benzamide |
| Synonyms: | CC671;CC 671 |
| 分子量: | 512.56 |
| 分子式: | C₂₈H₂₈N₆O₄ |
| SMILES: | O=C(NC)C1=CC=C(NC2=NC(NC=C3C4=CC(OC(C)=N5)=C5C=C4)=C3C(OC6CCCC6)=N2)C(OC)=C1 |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | CC-671 是一个双重 TTK 蛋白激酶/CDC2 样激酶 (CLK2) 抑制剂, 对于 TTK 和 CLK2 的IC50值分别为 0.005 和 0.006 μM。 |
| IC50和靶点: | [{name:"CLK2:0.006 μM (IC50)"}] |
| In Vitro: | |
| In Vivo: | |
| Clinical Trial: | |
| Solvent & Solubility: |
Riggs, J.R., Nagy, M., Elsner, J., et al.The discovery of a dual TTK protein kinase/CDC2-like kinase (CLK2) inhibitor for the treatment of triple negative breast cancer initiated from a phenotypic screenJ. Med. Chem.60(21),8989-9002(2017)
