Lerociclib dihydrochloride
Cat. No.：YN290127
CAS No. ：2097938-59-3
| 产品名称: | Lerociclib dihydrochloride |
| CAS No.: | 2097938-59-3 |
| Chemical Name: | |
| Synonyms: | G1T38 dihydrochloride |
| 分子量: | 547.52 |
| 分子式: | C₂₆H₃₆Cl₂N₈O |
| SMILES: | O=C1NCC2(N3C1=CC4=CN=C(NC5=NC=C(N6CCN(C(C)C)CC6)C=C5)N=C43)CCCCC2.[2HCl] |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | Lerociclib dihydrochloride (G1T38 dihydrochloride) 是一种有效的选择性CDK4/CDK6抑制剂，抑制CDK4/CyclinD1和CDK6/CyclinD3，IC50值分别为 1 nM 和 2 nM。 |
| IC50和靶点: | [{name:"Cdk4/cyclin D1:1 nM (IC50)"},{name: "cdk6/cyclin D3:2 nM (IC50)"},{name: "CDK9/Cyclin T:28 nM (IC50)"},{name: "CDK5/p35:832 nM (IC50)"},{name: "Cdk5/p25:1.2 μM (IC50)"},{name: "cdk2/cyclin A:1.5 μM (IC50)"},{name: "CDK2/cyclinE:3.6 μM (IC50)"},{name: "CDK1/cyclinB1:2.4 μM (IC50)"},{name: "CDK7/Cyclin H/MAT1:2.4 μM (IC50)"}] |
| In Vitro: | |
| In Vivo: | |
| Clinical Trial: | |
| Solvent & Solubility: |
