T025
Cat. No.：YN290129
CAS No. ：2407433-00-3
| 产品名称: | T025 |
| CAS No.: | 2407433-00-3 |
| Chemical Name: | |
| Synonyms: | |
| 分子量: | 382.42 |
| 分子式: | C₂₁H₁₈N₈ |
| SMILES: | CNC1=NC(NCC2=NC=CC=N2)=C(C(C3=CC=C(N=CC=C4)C4=C3)=CN5)C5=N1 |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | T025是有口服活性，高选择性的Cdc2-like 激酶 (CLK)抑制剂，对CLK1，CLK2，CLK3和CLK4的Kd分别为4.8，0.096，6.5和0.61 nM。 |
| IC50和靶点: | [{name:"CLK2:0.096 nM (Kd)"},{name: "CLK4:0.61 nM (Kd)"},{name: "CLK1:4.8 nM (Kd)"},{name: "CLK3:6.5 nM (Kd)"},{name: "DYRK1A:0.074 nM (Kd)"},{name: "DYRK1B:1.5 nM (Kd)"},{name: "DYRK2:32 nM (Kd)"}] |
| In Vitro: | |
| In Vivo: | |
| Clinical Trial: | |
| Solvent & Solubility: |
