SY-1365
Cat. No.：YN290220
CAS No. ：1816989-16-8
| 产品名称: | SY-1365 |
| CAS No.: | 1816989-16-8 |
| Chemical Name: | |
| Synonyms: | SY-1365 |
| 分子量: | 587.12 |
| 分子式: | C₃₁H₃₅ClN₈O₂ |
| SMILES: | O=C(C1=NC=C(NC(/C=C/CN(C)C)=O)C=C1)N[C@@]2(C)CCC[C@@H](NC3=NC=C(Cl)C(C4=CNC5=C4C=CC=C5)=N3)C2 |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | SY-1365 是一种高效、首创、选择性的CDK7抑制剂，其Ki值为 17.4 nM。SY-1365 在实体肿瘤细胞系中具有抗增殖和凋亡活性。SY-1365 具有抗血液肿瘤和侵袭性实体肿瘤作用。 |
| IC50和靶点: | |
| In Vitro: | |
| In Vivo: | |
| Clinical Trial: | |
| Solvent & Solubility: |
Rajagopal, N., et al.: PCT Int. Appl. (2018), WO 2018231859 A1 20181220
