NVP-LCQ195
Cat. No.:YN290340
CAS No. :902156-99-4
产品名称: | NVP-LCQ195 |
CAS No.: | 902156-99-4 |
Chemical Name: | |
Synonyms: | LCQ-195; AT9311 |
分子量: | 460.33 |
分子式: | C₁₇H₁₉Cl₂N₅O₄S |
SMILES: | CS(=O)(N1CCC(NC(C2=C(NC(C3=C(Cl)C=CC=C3Cl)=O)C=NN2)=O)CC1)=O |
存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
运输: | Room temperature in continental US; may vary elsewhere. |
产品描述: | NVP-LCQ195 (AT9311; LCQ195)是CDK杂环类抑制剂,对CDK1,CDK2,CDK3和CDK5的IC50为1-42 nM。 |
IC50和靶点: | [{name:"Cdk5/p25:1 nM (IC50)"},{name: "CDK5/p35:1 nM (IC50)"},{name: "Cdk1/cyclin B:2 nM (IC50)"},{name: "cdk2/cyclin A:2 nM (IC50)"},{name: "CDK2/cyclinE:5 nM (IC50)"},{name: "CDK9/cyclinT1:15 nM (IC50)"},{name: "CDK3/Cyclin E:42 nM (IC50)"},{name: "cdk6/cyclin D3:187 nM (IC50)"},{name: "CDK7/Cyclin H/MAT1:3564 nM (IC50)"}] |
In Vitro: | |
In Vivo: | |
Clinical Trial: | |
Solvent & Solubility: |