Ribociclib succinate hydrate
Cat. No.：YN290372
CAS No. ：1374639-79-8
| 产品名称: | Ribociclib succinate hydrate |
| CAS No.: | 1374639-79-8 |
| Chemical Name: | |
| Synonyms: | LEE011 succinate hydrate |
| 分子量: | 570.64 |
| 分子式: | C₂₇H₃₈N₈O₆ |
| SMILES: | O=C(N(C)C)C(N1C2CCCC2)=CC(C1=N3)=CN=C3NC(N=C4)=CC=C4N5CCNCC5.OC(CCC(O)=O)=O.[F,Cl,Br,I].O |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | Ribociclib succinate hydrate (LEE011 succinate hydrate) 是一种高度特异性的CDK4/6抑制剂，IC50值分别为 10 nM 和 39 nM，对 cyclin B/CDK1 复合体的活性低于其 1000 倍。 |
| IC50和靶点: | [{name:"CDK4:10 nM (IC50)"},{name: "CDK6:39 nM (IC50)"}] |
| In Vitro: | |
| In Vivo: | |
| Clinical Trial: | |
| Solvent & Solubility: |
