ML167
Cat. No.：YN290379
CAS No. ：1285702-20-6
| 产品名称: | ML167 |
| CAS No.: | 1285702-20-6 |
| Chemical Name: | 5-[4-[[(5-methyl-2-furanyl)methyl]amino]-6-quinazolinyl]-2-furanmethanol |
| Synonyms: | CID44968231; NCGC00188654 |
| 分子量: | 335.36 |
| 分子式: | C₁₉H₁₇N₃O₃ |
| SMILES: | OCC1=CC=C(C2=CC3=C(NCC4=CC=C(C)O4)N=CN=C3C=C2)O1 |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | ML167 是一种高度选择性的 Cdc2 样激酶 4 (Clk4) 抑制剂，IC50为 136 nM，比作用于相关激酶Clk1，Clk2，Clk3 和 Dyrk1A/1B 的选择性高 10 多倍。 |
| IC50和靶点: | [{name:"CLK4:136 nM (IC50)"},{name: "CLK1:1522 nM (IC50)"},{name: "CLK2:1648 nM (IC50)"},{name: "DYRK1B:4420 nM (IC50)"},{name: "CDK3:＞10000 nM (IC50)"},{name: "DYRK1A:＞10000 nM (IC50)"}] |
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| In Vivo: | |
| Clinical Trial: | |
| Solvent & Solubility: |
Rosenthal, A.S., Tanega, C., Shen, M., et al.An inhibitor of the Cdc2-like kinase 4 (Clk4)Probe Reports from the NIH Molecular Libraries Program,(2010)
