PG01
Cat. No.：YN360134
| 产品名称: | PG01 |
| CAS No.: | 853138-65-5 |
| Chemical Name: | |
| Synonyms: | Phenylglycine-01 |
| 分子量: | 439.55 |
| 分子式: | C₂₈H₂₉N₃O₂ |
| SMILES: | O=C(N(C)C(C1=CC=CC=C1)C(NC2=CC=C(C(C)C)C=C2)=O)CC3=CNC4=C3C=CC=C4 |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | PG01 是一种有效的CFTRCl-通道增效剂。PG01 对E193K，G970R和G551D(CFTR突变体) 有效，Kd值分别为 0.22 μM，0.45 μM 和 1.94 μM。PG01对ΔF508（Ka为 0.3 μM）也有效。PG01 在添加 Forskolin 后增加ΔF508-CFTRCl-电流。 |
| IC50和靶点: | |
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| Clinical Trial: | |
| Solvent & Solubility: |
