IOWH-032
Cat. No.：YN360651
CAS No. ：1191252-49-9
| 产品名称: | IOWH-032 |
| CAS No.: | 1191252-49-9 |
| Chemical Name: | 3-(3,5-dibromo-4-hydroxyphenyl)-N-[(4-phenoxyphenyl)methyl]-1,2,4-oxadiazole-5-carboxamide |
| Synonyms: | IOWH032,IOWH 032 |
| 分子量: | 545.18 |
| 分子式: | C₂₂H₁₅Br₂N₃O₄ |
| SMILES: | BrC1=C(O)C(Br)=CC(C2=NOC(C(NCC3=CC=C(OC4=CC=CC=C4)C=C3)=O)=N2)=C1 |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | IOWH-032是CFTR抑制剂，在T84和CHO-CFTR细胞实验中IC50为1.01 uM。 |
| IC50和靶点: | |
| In Vitro: | |
| In Vivo: | |
| Clinical Trial: | |
| Solvent & Solubility: |
Doyle, K.J., Jones, G.P., Russell, M.G.N., et al.Compounds, compositions and methods compromising heteroaromatic derivatesUS2009/0318429Al,(2009)
Cui, G., Khazanov, N., Stauffer, B.B., et al.Potentiators exert distinct effects on human, murine, and Xenopus CFTRAm. J. Physiol. Lung. Cell. Mol. Physiol.311(2),L192-207(2016)
