KM11060
Cat. No.：YN360698
CAS No. ：774549-97-2
| 产品名称: | KM11060 |
| CAS No.: | 774549-97-2 |
| Chemical Name: | 7-chloro-4-[4-[(4-chlorophenyl)sulfonyl]-1-piperazinyl]-quinoline |
| Synonyms: | KM 11060;7-CHLORO-4-(4-(4-CHLOROPHENYLSULFONYL)PIPERAZIN-1-YL)QUINOLINE;7-chloro-4-[4-(4-chlorophenyl)sulfonylpiperazin-1-yl]quinoline;7-Chloro-4-{4-[(4-chlorophenyl)sulfonyl]piperazin-1-yl}quinoline;7-chloro-4-{4-[(4-chlorophenyl)sulfonyl]piperazino}quin |
| 分子量: | 422.33 |
| 分子式: | C₁₉H₁₇Cl₂N₃O₂S |
| SMILES: | O=S(N1CCN(C2=CC=NC3=CC(Cl)=CC=C23)CC1)(C4=CC=C(Cl)C=C4)=O |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | KM11060 是 F508 缺失-囊性纤维化跨膜电导调节剂 (F508del-CFTR) 转运缺陷的校正剂。 KM11060 可用于 F508del-CFTR 加工缺陷的研究和囊性纤维化治疗剂的开发。 |
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| Solvent & Solubility: |
Robert, R., Carlile, G.W., Pavel, C., et al.Structural analog of sildenafil identified as a novel corrector of the F508del-CFTR trafficking defectMol. Pharmacol.73(2),478-489(2008)
