Enocitabine
Cat. No.:YN250336
产品名称: | Enocitabine |
CAS No.: | 55726-47-1 |
Chemical Name: | N-(1-β-D-arabinofuranosyl-1,2-dihydro-2-oxo-4-pyrimidinyl)-docosanamide |
Synonyms: | 依诺他滨 |
分子量: | 565.78 |
分子式: | C₃₁H₅₅N₃O₆ |
SMILES: | CCCCCCCCCCCCCCCCCCCCCC(NC(C=CN1[C@H]2[C@@H](O)[C@H](O)[C@H](O2)CO)=NC1=O)=O |
存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
运输: | Room temperature in continental US; may vary elsewhere. |
产品描述: | Enocitabine 是一种核苷类似物,是一种有效的 DNA 复制抑制剂和 DNA链终止剂。Enocitabine 抑制人巨细胞病毒的复制,具有抗白血病和抗病毒活性。 |
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Higashigawa, M., Ochiai, H., Ohkubo, T., et al.Incorporation of N4-behenoyl-1-β-ᴅ-arabinofuranosylcytosine into DNA as 1-β-ᴅ-arabinofuranosylcytosineMed. Oncol. Tumor Pharmacother.5(4),265-271(1988)
Aoshima, M., Tsukagoshi, S., Sakurai, Y., et al.N4-Behenoyl-1-β-ᴅ-arabinofuranosylcytosine as a potential new antitumor agentCancer Res.37(8 Pt. 1),2481-2486(1977)
Nakamura, K., Eizuru, Y., Kumura, K., et al.Antiviral effect of antileukemic drugs N4-behenoyl-1-beta-D-arabinofuranosylcytosine (BH-AC) and 2,2'-anhydro-1-beta-D-arabinofuranosylcytosine (cyclo-C) against human cytomegalovirusJ. Med. Virol.31(2),141-147(1990)