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Enocitabine

Cat. No.:YN250336

  • CAS No. :55726-47-1

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    • 参考文献
    • 产品名称: Enocitabine
      CAS No.: 55726-47-1
      Chemical Name: N-(1-β-D-arabinofuranosyl-1,2-dihydro-2-oxo-4-pyrimidinyl)-docosanamide
      Synonyms:依诺他滨
      分子量:565.78
      分子式:C₃₁H₅₅N₃O₆
      SMILES:CCCCCCCCCCCCCCCCCCCCCC(NC(C=CN1[C@H]2[C@@H](O)[C@H](O)[C@H](O2)CO)=NC1=O)=O
      存储:Please store the product under the recommended conditions in theCertificate of Analysis.
      运输:Room temperature in continental US; may vary elsewhere.
      Select Batch:
      Purity: 98%
    • 产品描述: Enocitabine 是一种核苷类似物,是一种有效的 DNA 复制抑制剂和 DNA链终止剂。Enocitabine 抑制人巨细胞病毒的复制,具有抗白血病和抗病毒活性。
      IC50和靶点:
      In Vitro:
      In Vivo:
      Clinical Trial:
      Solvent & Solubility:
    • Higashigawa, M., Ochiai, H., Ohkubo, T., et al.Incorporation of N4-behenoyl-1-β-ᴅ-arabinofuranosylcytosine into DNA as 1-β-ᴅ-arabinofuranosylcytosineMed. Oncol. Tumor Pharmacother.5(4),265-271(1988)

      Aoshima, M., Tsukagoshi, S., Sakurai, Y., et al.N4-Behenoyl-1-β-ᴅ-arabinofuranosylcytosine as a potential new antitumor agentCancer Res.37(8 Pt. 1),2481-2486(1977)

      Nakamura, K., Eizuru, Y., Kumura, K., et al.Antiviral effect of antileukemic drugs N4-behenoyl-1-beta-D-arabinofuranosylcytosine (BH-AC) and 2,2'-anhydro-1-beta-D-arabinofuranosylcytosine (cyclo-C) against human cytomegalovirusJ. Med. Virol.31(2),141-147(1990)

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