Brivudine
Cat. No.:YN250496
产品名称: | Brivudine |
CAS No.: | 69304-47-8 |
Chemical Name: | 5-[(1E)-2-bromoethenyl]-2′-deoxy-uridine |
Synonyms: | 溴夫定; Bromovinyldeoxyuridine; BVDU |
分子量: | 333.14 |
分子式: | C₁₁H₁₃BrN₂O₅ |
SMILES: | OC[C@@H]1[C@H](C[C@H](N2C(NC(C(/C=C/Br)=C2)=O)=O)O1)O |
存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
运输: | Room temperature in continental US; may vary elsewhere. |
产品描述: | Brivudine是具有抗病毒活性的胸苷类似物,用于早期急性带状疱疹的研究。 |
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De Clercq, E., Desgranges, C., Herdewijn, P., et al.Synthesis and antiviral activity of (E)-5-(2-bromovinyl)uracil and (E)-5-(2-bromovinyl)uridineJ. Med. Chem.29(2),213-217(1986)
Kulikowski, T.Structure-activity relationships and conformational features of antiherpetic pyrimidine and purine nucleoside analogues. A reviewPharm. World Sci.16(2),127-138(1994)
De Clercq, E., Descamps, J., Verhelst, G., et al.Antiviral activity of 5-(2-halogenovinyl)-2'-deoxyuridinesCurr. Chemother. Infect. Dis.2,1372-1374(1980)