Letermovir
Cat. No.：YN250624
CAS No. ：917389-32-3
| 产品名称: | Letermovir |
| CAS No.: | 917389-32-3 |
| Chemical Name: | (4S)-8-fluoro-3,4-dihydro-2-[4-(3-methoxyphenyl)-1-piperazinyl]-3-[2-methoxy-5-(trifluoromethyl)phenyl]-4-quinazolineacetic acid |
| Synonyms: | 莱莫维韦; AIC246 |
| 分子量: | 572.55 |
| 分子式: | C₂₉H₂₈F₄N₄O₄ |
| SMILES: | FC1=C(N=C(N2CCN(C3=CC=CC(OC)=C3)CC2)N(C4=CC(C(F)(F)F)=CC=C4OC)[C@H]5CC(O)=O)C5=CC=C1 |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | Letermovir 是一种新颖的CMV抑制剂，以病毒末端酶为靶目标，抑制其活性。 |
| IC50和靶点: | |
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| Solvent & Solubility: |
Marschall, M., Stamminger, T., Urban, A., et al.In vitro evaluation of the activities of the novel anticytomegalovirus compound AIC246 (letermovir) against herpesviruses and other human pathogenic virusesAntimicrob. Agents Chemother.56(2),1135-1137(2012)
Goldner, T., Hewlett, G., Ettischer, N., et al.The novel anticytomegalovirus compound AIC246 (Letermovir) inhibits human cytomegalovirus replication through a specific antiviral mechanism that involves the viral terminaseJ. Virol.85(20),10884-10893(2011)
