R121919
Cat. No.：YN320818
CAS No. ：195055-03-9
| 产品名称: | R121919 |
| CAS No.: | 195055-03-9 |
| Chemical Name: | NBI 30775; R 121919; R 121919 (Neurocrine Biosciences Inc.); |
| Synonyms: | NBI30775 |
| 分子量: | 380.53 |
| 分子式: | C₂₂H₃₂N₆ |
| SMILES: | CCCN(C1=CC(C)=NC2=C(C3=CN=C(N(C)C)C=C3C)C(C)=NN21)CCC |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | R121919 (NBI30775) 是一种高效的小分子CRF1受体拮抗剂。对于 CRF1 受体的Ki值为 2 至 5 nM，对 CRF2 受体，CRF 结合蛋白或 70 种其它受体类型的活性弱超过 1000 倍。 |
| IC50和靶点: | |
| In Vitro: | |
| In Vivo: | |
| Clinical Trial: | |
| Solvent & Solubility: |
Takahashi, Y., et al.: J. Med. Chem., 55, 8450 (2012)
Zorrilla, E., Drug and Alcohol Dependence, 128, 175 (2013)
