Antileukinate
Cat. No.：YN320609
| 产品名称: | Antileukinate |
| CAS No.: | 138559-60-1 |
| Chemical Name: | N2-acetyl-L-arginyl-L-arginyl-L-tryptophyl-L-tryptophyl-L-cysteinyl-L-argininamide |
| Synonyms: | Ac-RRWWCR-NH2 |
| 分子量: | 1003.19 |
| 分子式: | C₄₅H₆₆N₁₈O₇S |
| SMILES: | 暂无 |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | Antileukinate 是一种六肽，是有效的 CXC 趋化因子受体 (CXCR) 抑制剂。Antileukinate 能抑制中性粒细胞趋化和活化。Antileukinate 可用于急性炎症和损伤的研究。 |
| IC50和靶点: | |
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Fujisawa, N., Hayashi, S., Kurdowska, A., et al.Inhibition of GROα-induced human endothelial cell proliferation by the α-chemokine inhibitor antileukinateCytokine11(3),231-238(1999)
Bhatia, M., and Hegde, A.Treatment with antileukinate, a CXCR2 chemokine receptor antagonist, protects mice against acute pancreatitis and associated lung injuryRegul. Pept.138(1),40-48(2007)
Hirayama, S., Shiraishi, T., Shirakusa, T., et al.Prevention of neutrophil migration ameliorates rat lung allograft rejectionMol. Med.12(9-10),208-213(2006)
Hayashi, S., Kurdowska, A., Cohen, A.B., et al.A synthetic peptide inhibitor for α-chemokines inhibits the growth of melanoma cell linesJ. Clin. Invest.99(11),2581-2587(1997)
Hayashi, S., Kurdowska, A., Miller, E.J., et al.Synthetic hexa- and heptapeptides that inhibit IL-8 from binding to and activating human blood neutrophilsJ. Immunol.154(2),814-824(1995)
