Elubrixin tosylate
Cat. No.:YN321182
CAS No. :960495-43-6
产品名称: | Elubrixin tosylate |
CAS No.: | 960495-43-6 |
Chemical Name: | |
Synonyms: | SB-656933 tosylate |
分子量: | 635.51 |
分子式: | C₂₄H₂₅Cl₂FN₄O₇S₂ |
SMILES: | O=C(NC1=CC=C(Cl)C(S(=O)(N2CCNCC2)=O)=C1O)NC3=CC=CC(F)=C3Cl.OS(=O)(C4=CC=C(C)C=C4)=O |
存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
运输: | Room temperature in continental US; may vary elsewhere. |
产品描述: | Elubrixin tosylate (SB-656933 tosylate) 是一种有效,选择性,竞争性,可逆和具有口服活性的CXCR2拮抗剂和IL-8受体拮抗剂。Elubrixin tosylate 抑制中性粒细胞 CD11b 上调 (IC50为 260.7 nM) 和形状改变 (IC50为 310.5 nM)。Elubrixin tosylate 可用于炎症性疾病的研究,例如炎症性肠病和气道炎症。 |
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