Danirixin
Cat. No.：YN321245
CAS No. ：954126-98-8
| 产品名称: | Danirixin |
| CAS No.: | 954126-98-8 |
| Chemical Name: | N-[4-chloro-2-hydroxy-3-[(3S)-3-piperidinylsulfonyl]phenyl]-N'-(3-fluoro-2-methylphenyl)-urea |
| Synonyms: | GSK1325756 |
| 分子量: | 441.90 |
| 分子式: | C₁₉H₂₁ClFN₃O₄S |
| SMILES: | O=C(NC1=CC=C(Cl)C(S([C@H]2CCCNC2)(=O)=O)=C1O)NC3=C(C)C(F)=CC=C3 |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | Danirixin 是选择性，可逆的CXCR2拮抗剂。抑制 CXCL8的IC50值为 12.5 nM。 |
| IC50和靶点: | [{name:"CXCL8-CXCR2:12.5 nM (IC50)"}] |
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| Solvent & Solubility: |
Busch-Petersen, J., Carpenter, D.C., Burman, M., et al.Danirixin: A reversible and selective antagonist of the CXC chemokine receptor 2J. Pharmacol. Exp. Ther.362(2),338-346(2017)
