Motixafortide
Cat. No.：YN321794
CAS No. ：664334-36-5
| 产品名称: | Motixafortide |
| CAS No.: | 664334-36-5 |
| Chemical Name: | N2-(4-fluorobenzoyl)-L-arginyl-L-arginyl-3-(2-naphthalenyl)-L-alanyl-L-cysteinyl-L-tyrosyl-N5-(aminocarbonyl)-L-ornithyl-L-lysyl-D-lysyl-L-prolyl-L-tyrosyl-L-arginyl-N5-(aminocarbonyl)-L-ornithyl-L-cysteinyl-L-argininamide, cyclic (4→13)-disulfide |
| Synonyms: | BKT140 (4-fluorobenzoyl); BL-8040; TF14016 |
| 分子量: | 2159.52 |
| 分子式: | C₉₇H₁₄₄FN₃₃O₁₉S₂ |
| SMILES: | [4F-Benzoyl-RR-{2-Naph-Ala}-CY-{Cit}-KKPYR-{Cit}-CR-NH2_x000D_(Disulfide bridge: Cys4-Cys13)] |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | Motixafortide (BKT140 4-fluorobenzoyl) 是一种新型的CXCR4拮抗剂，IC50约为1 nM。 |
| IC50和靶点: | [{name:"CXCR4:~1 nM (IC50)"}] |
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| Solvent & Solubility: |
Tamamura, H., Hori, A., Kanzaki, N., et al.T140 analogs as CXCR4 antagonists identified as anti-metastatic agents in the treatment of breast cancerFEBS Lett.550(1-3),79-83(2003)
Beider, K., Begin, M., Abraham, M., et al.CXCR4 antagonist 4F-benzoyl-TN14003 inhibits leukemia and multiple myeloma tumor growthExp. Hematol.39(3),282-292(2011)
Tamamura, H., Fujisawa, M., Hiramatsu, K., et al.Identification of a CXCR4 antagonist, a T140 analog, as an anti-rheumatoid arthritis agentFEBS Lett.569(1-3),99-104(2004)
