A-484954
Cat. No.：YN380038
CAS No. ：142557-61-7
| 产品名称: | A-484954 |
| CAS No.: | 142557-61-7 |
| Chemical Name: | 7-amino-1-cyclopropyl-3-ethyl-1,2,3,4-tetrahydro-2,4-dioxo-pyrido[2,3-d]pyrimidine-6-carboxamide |
| Synonyms: | A 484954 |
| 分子量: | 289.29 |
| 分子式: | C₁₃H₁₅N₅O₃ |
| SMILES: | O=C(N1CC)N(C2CC2)C3=C(C=C(C(N)=O)C(N)=N3)C1=O |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | A-484954 是真核延长因子 2(eEF2)的高度选择性抑制剂，其IC50值为 280 nM。 |
| IC50和靶点: | |
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| Solvent & Solubility: |
Edupuganti, R., Wang, Q., Tavares, C.D., et al.Synthesis and biological evaluation of pyrido[2,3-d]pyrimidine-2,4-dione derivatives as eEF-2K inhibitorsBioorg. Med. Chem.22(17),4910-4916(2014)
