Cinacalcet hydrochloride
Cat. No.：YN321293
CAS No. ：364782-34-3
| 产品名称: | Cinacalcet hydrochloride |
| CAS No.: | 364782-34-3 |
| Chemical Name: | αR-methyl-N-[3-[3-(trifluoromethyl)phenyl]propyl]-1-naphthalenemethanamine, monohydrochloride |
| Synonyms: | 盐酸西那卡塞; AMG-073 hydrochloride |
| 分子量: | 393.87 |
| 分子式: | C₂₂H₂₃ClF₃N |
| SMILES: | FC(F)(C1=CC(CCCN[C@@H](C2=C3C=CC=CC3=CC=C2)C)=CC=C1)F.Cl |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | Cinacalcet hydrochloride (AMG 073 hydrochloride) 是一种可口服的Ca receptor (CaR)激动剂，用于心血管疾病研究。 |
| IC50和靶点: | |
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| Solvent & Solubility: |
Ma, J.N., Owens, M., Gustafsson, M., et al.Characterization of highly efficacious allosteric agonists of the human calcium-sensing receptorJ. Pharmacol. Exp. Ther.337(1),275-284(2011)
Imanishi, Y., Kawata, T., Kenko, T., et al.Cinacalcet HCl suppresses Cyclin D1 oncogene-derived parathyroid cell proliferation in a murine model for primary hyperparathyroidismCalcif. Tissue Int.89(1),29-35(2011)
