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Ligustroflavone

Cat. No.:YN321722

  • CAS No. :260413-62-5

    • 产品资料
    • 生物活性
    • 参考文献
    • 产品名称: Ligustroflavone
      CAS No.: 260413-62-5
      Chemical Name: 7-[(O-6-deoxy-α-L-mannopyranosyl-(1→2)-O-[6-deoxy-α-L-mannopyranosyl-(1→6)]-β-D-glucopyranosyl)oxy]-5-hydroxy-2-(4-hydroxyphenyl)-4H-1-benzopyran-4-one
      Synonyms:女贞苷; Nuezhenoside
      分子量:724.66
      分子式:C₃₃H₄₀O₁₈
      SMILES:O=C(C=C(C1=CC=C(O)C=C1)OC2=CC(O[C@H](O[C@H](CO[C@H](O[C@@H](C)[C@H](O)[C@H]3O)[C@@H]3O)[C@@H](O)[C@@H]4O)[C@@H]4O[C@@](O[C@@H](C)[C@H](O)[C@H]5O)([H])[C@@H]5O)=C6)C2=C6O
      存储:Please store the product under the recommended conditions in theCertificate of Analysis.
      运输:Room temperature in continental US; may vary elsewhere.
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      Purity: 98%
    • 产品描述: Ligustroflavone 可从Ligustrum lucidum中提取得到,是一种潜在的钙敏感受体(CaSR)拮抗剂。Ligustroflavone对糖尿病性骨质疏松症小鼠有保护作用。
      IC50和靶点:
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    • Pieroni, A., and Pachaly, P.Isolation and structure elucidation of ligustroflavone, a new apigenin triglycoside from the leaves of Ligustrum vulgare L.Pharmazie55(1),78-80(2000)

      Feng, R., Ding, F., Mi, X.-H., et al.Protective effects of ligustroflavone, an active compound from Ligustrum lucidum, on diabetes-induced osteoporosis in mice: A potential candidate as calcium-sensing receptor antagonistAm. J. Chin. Med.47(2),457-476(2019)

      Zhang, Y.-Y., Liu, W.-N., Li, Y.-Q., et al.Ligustroflavone reduces necroptosis in rat brain after ischemic stroke through targeting RIPK1/RIPK3/MLKL pathwayNaunyn Schmiedebergs Arch. Pharmacol.392(9),1085-1095(2019)

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