Norverapamil hydrochloride
Cat. No.：YN360047
| 产品名称: | Norverapamil hydrochloride |
| CAS No.: | 67812-42-4 |
| Chemical Name: | α-[3-[[2-(3,4-dimethoxyphenyl)ethyl]amino]propyl]-3,4-dimethoxy-α-(1-methylethyl)-benzeneacetonitrile, monohydrochloride |
| Synonyms: | 盐酸去甲维拉帕米; (±) |
| 分子量: | 477.04 |
| 分子式: | C₂₆H₃₇ClN₂O₄ |
| SMILES: | N#CC(C(C)C)(CCCNCCC1=CC=C(OC)C(OC)=C1)C2=CC=C(OC)C(OC)=C2.[H]Cl |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | Norverapamil hydrochloride，是 Verapamil 的 N-去甲基代谢物，是一种钙通道 (L-type calcium channel) 阻滞剂和 P-糖蛋白 (P-gp) 功能抑制剂。 |
| IC50和靶点: | |
| In Vitro: | |
| In Vivo: | |
| Clinical Trial: | |
| Solvent & Solubility: |
Tracy, T.S., Korzekwa, K.R., Gonzalez, F.J., et al.Cytochrome P450 isoforms involved in metabolism of the enantiomers of verapamil and norverapamilBr. J. Clin. Pharmacol.47(5),545-552(1999)
Abate, G., Ruminiski, P.G., Kumar, M., et al.New verapamil analogs inhibit intracellular mycobacteria without affecting the functions of Mycobacterium-specific T cellsAntimicrob. Agents Chemother.60(3),1216-1225(2015)
