MRS1845
Cat. No.：YN360129
CAS No. ：544478-19-5
| 产品名称: | MRS1845 |
| CAS No.: | 544478-19-5 |
| Chemical Name: | 1,4-dihydro-2,6-dimethyl-4-(3-nitrophenyl)-1-(2-propyn-1-yl)-3,5-pyridinedicarboxylic acid, 3-ethyl 5-methyl ester |
| Synonyms: | MRS-1845，MRS1845，MRS 1845 |
| 分子量: | 398.41 |
| 分子式: | C₂₁H₂₂N₂O₆ |
| SMILES: | O=C(C1=C(C)N(CC#C)C(C)=C(C(OC)=O)C1C2=CC=CC([N+]([O-])=O)=C2)OCC |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | MRS1845 是一种选择性钙池调控钙离子通道 (SOC) 抑制剂，IC50为 1.7 μM。MRS1845 是一种ORAI1抑制剂。 |
| IC50和靶点: | |
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| Clinical Trial: | |
| Solvent & Solubility: |
Harper, J.L., Camerini-Otero, C.S., Li, A.-H., et al.Dihydropyridines as inhibitors of capacitative calcium entry in leukemic HL-60 cellsBiochem. Pharmacol.65(3),329-338(2003)
Lee, C., Xu, D.-Z., Feketeova, E., et al.Calcium entry inhibition during resuscitation from shock attenuates inflammatory lung injuryShock30(1),29-35(2008)
