Tetrabenazine Metabolite
Cat. No.:YN361536
产品名称: | Tetrabenazine Metabolite |
CAS No.: | 924854-60-4 |
Chemical Name: | (2S,3R,11bR)-1,3,4,6,7,11b-Hexahydro-9,10-dimethoxy-3-(2-methylpropyl)-2H-benzo[a]quinolizin-2-ol; (2S,3R,11bR)-Dihydrotetrabe |
Synonyms: | |
分子量: | 319.445 |
分子式: | C19H29NO3 |
SMILES: | 暂无 |
存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
运输: | Room temperature in continental US; may vary elsewhere. |
产品描述: | Tetrabenazine Metabolite ((-)-β-Dihydrotetrabenazine) 是 Tetrabenazine 的一种活性代谢物。Tetrabenazine Metabolite 是一种囊泡单胺转运蛋白 2 (VMAT2) 抑制剂。对 VMAT2 具有高亲和力,Ki=13.4 nM。Tetrabenazine Metabolite 可用于研究与亨廷顿氏病和其他多动障碍相关的舞蹈病。 |
IC50和靶点: | |
In Vitro: | |
In Vivo: | |
Clinical Trial: | |
Solvent & Solubility: |
Yao, Z., et al.: Eur. J. Med. Chem., 46, 1841 (2011)
Rishel, M.J., et al.: J. Org. Chem., 74, 4001 (2009)