A-836339
Cat. No.：YN320639
| 产品名称: | A-836339 |
| CAS No.: | 959746-77-1 |
| Chemical Name: | [N(Z)]-N-[3-(2-methoxyethyl)-4,5-dimethyl-2(3H)-thiazolylidene]-2,2,3,3-tetramethyl-cyclopropanecarboxamide |
| Synonyms: | A836339 |
| 分子量: | 310.45 |
| 分子式: | C₁₆H₂₆N₂O₂S |
| SMILES: | CC1=C(C)S/C(N1CCOC)=N\C(C2C(C)(C)C2(C)C)=O |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | A-836339是CB2受体选择性激动剂，对CB1受体作用基本无。 |
| IC50和靶点: | |
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| Solvent & Solubility: |
Yao, B.B., Hsieh, G., Daza, A.V., et al.Characterization of a cannabinoid CB2 receptor-selective agonist, A-836339 [2,2,3,3-tetramethyl-cyclopropanecarboxylic acid [3-(2-methoxy-ethyl)-4,5-dimethyl-3H-thiazol-(2Z)-ylidene]-amide], using in vitro pharmacological assays, in vivo pain models, and pharmacological magnetic resonance imagingJ. Pharmacol. Exp. Ther.328(1),141-151(2009)
McGaraughty, S., Chu, K.L., Dart, M.J., et al.A CB2 receptor agonist, A-836339, modulates wide dynamic range neuronal activity in neuropathic rats: Contributions of spinal and peripheral CB2 receptorsNeuroscience158(4),1652-1661(2009)
