SR144528
Cat. No.：YN320735
CAS No. ：192703-06-3
| 产品名称: | SR144528 |
| CAS No.: | 192703-06-3 |
| Chemical Name: | 5-(4-chloro-3-methylphenyl)-1-[(4-methylphenyl)methyl]-N-[(1S,2S,4R)-1,3,3-trimethylbicyclo[2.2.1]hept-2-yl]-1H-pyrazole-3-carboxamide |
| Synonyms: | SR-144528;SR144528 |
| 分子量: | 476.05 |
| 分子式: | C₂₉H₃₄ClN₃O |
| SMILES: | O=C(C1=NN(CC2=CC=C(C)C=C2)C(C3=CC=C(Cl)C(C)=C3)=C1)N[C@H]4[C@@](C5)(C)CC[C@@]5([H])C4(C)C |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | SR144528 是一个有效且选择性的CB2受体拮抗剂，其Ki值为 0.6 nM。 |
| IC50和靶点: | |
| In Vitro: | |
| In Vivo: | |
| Clinical Trial: | |
| Solvent & Solubility: |
Pertwee, R.G.Pharmacology of cannabinoid receptor ligandsCurr. Med. Chem.6(8),635-664(1999)
Rinaldi-Carmona, M., Barth, F., Millan, J., et al.SR 144528, the first potent and selective antagonist of the CB2 cannabinoid receptorJ. Pharmacol. Exp. Ther.284(2),644-650(1998)
Iwamura, H., Suzuki, H., Ueda, Y., et al.In vitro and in vivo pharmacological characterization of JTE-907, a novel selection ligand for cannabinoid CB2 receptorJ. Pharmacol. Exp. Ther.296(2),420-425(2001)
