(±)-Ibipinabant
Cat. No.：YN320914
CAS No. ：362519-49-1
| 产品名称: | (±)-Ibipinabant |
| CAS No.: | 362519-49-1 |
| Chemical Name: | 3-(4-chlorophenyl)-N-[(4-chlorophenyl)sulfonyl]-4,5-dihydro-N'-methyl-4-phenyl-1H-pyrazole-1-carboximidamide |
| Synonyms: | (±)-SLV319; (±)-BMS6462 |
| 分子量: | 487.40 |
| 分子式: | C₂₃H₂₀Cl₂N₄O₂S |
| SMILES: | C/N=C(N1N=C(C2=CC=C(Cl)C=C2)C(C3=CC=CC=C3)C1)\NS(=O)(C4=CC=C(Cl)C=C4)=O |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | (±)-Ibipinabant ((±)-SLV319) 是SLV319的消旋体。(±)-Ibipinabant ((±)-SLV319) 是有效选择性的大麻素-1 (CB-1) 受体拮抗剂，IC50值为22 nM。 |
| IC50和靶点: | |
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Lange, J.H.M., Coolen, H.K.A.C., van Stuivenberg, H.H., et al.Synthesis, biological properties, and molecular modeling investigations of novel 3,4-diarylpyrazolines as potent and selective CB1 cannabinoid receptor antagonistsJ. Med. Chem.47(3),627-643(2004)
Lange, J.H.M., van Stuivenberg, H.H., Veerman, W., et al.Novel 3,4-diarylpyrazolines as potent cannabinoid CB1 receptor antagonists with lower lipophilicityBioorg. Med. Chem. Lett.15,4794-4798(2005)
