MDA 19
Cat. No.：YN320992
| 产品名称: | MDA 19 |
| CAS No.: | 1048973-47-2 |
| Chemical Name: | (2Z)-2-(1-hexyl-1,2-dihydro-2-oxo-3H-indol-3-ylidene)hydrazide, benzoic acid |
| Synonyms: | MDA19; MDA-19 |
| 分子量: | 349.43 |
| 分子式: | C₂₁H₂₃N₃O₂ |
| SMILES: | O=C(N/N=C1C(N(CCCCCC)C2=C\1C=CC=C2)=O)C3=CC=CC=C3 |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | MDA 19 是一种有效和选择性的人类大麻素受体 2 (CB2) 激动剂，Ki值为 43.3 nM。MDA 19 在神经性疼痛的大鼠模型中具有抗痛觉过敏作用，并且不影响大鼠的运动能力。 |
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Deventer, M.H., Van Uytfanghe, K., Vinckier, I.M.J., et al.Cannabinoid receptor activation potential of the next generation, generic ban evading OXIZID synthetic cannabinoid receptor agonistsDrug Test Anal.,(2022)
Diaz, P., Xu, J., Astruc-Diaz, F., et al.Design and synthesis of a novel series of N-alkyl isatin acylhydrazone derivatives that act as selective cannabinoid receptor 2 agonists for the treatment of neuropathic painJ. Med. Chem.51(16),4932-4947(2008)
Xu, J.J., Diaz, P., Astruc-Diaz, F., et al.Pharmacological characterization of a novel cannabinoid ligand, MDA19, for treatment of neuropathic painAnesth. Analg.111(1),99-109(2010)
