Pregnenolone
Cat. No.：YN321395
| 产品名称: | Pregnenolone |
| CAS No.: | 145-13-1 |
| Chemical Name: | 3β-hydroxy-pregn-5-en-20-one |
| Synonyms: | 孕烯醇酮; 3β-Hydroxy-5-pregnen-20-one |
| 分子量: | 316.48 |
| 分子式: | C₂₁H₃₂O₂ |
| SMILES: | C[C@@](C1=CC2)(CC[C@H](O)C1)[C@]3([H])[C@]2([H])[C@@](CC[C@@H]4C(C)=O)([H])[C@]4(C)CC3 |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | Pregnenolone (3β-Hydroxy-5-pregnen-20-one) 是一种功能强大的神经甾体，是包括甾体酮在内的各种甾体激素的主要前体。Pregnenolone 是大麻素CB1受体的信号传导特异性抑制剂，抑制由CB1受体介导的四氢大麻酚 (THC) 的作用。Pregnenolone 可以保护大脑免受大麻中毒。 |
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Sedláček, M., Kořínek, M., Petrovič, M., et al.Neurosteroid modulation of ionotropic glutamate receptors and excitatory synaptic transmissionPhysiol. Res.57(Suppl 3),S49-S57(2008)
Smith, C.C., Gibbs, T.T., and Farb, D.H.Pregnenolone sulfate as a modulator of synaptic plasticityPsychopharmacology (Berl)231(17),3537-3556(2014)
Thiel, G., Müller, I., and Rössler, O.G.Signal transduction via TRPM3 channels in pancreatic β-cellsJ. Mol. Endocrinol.50(3),R75-R83(2013)
