Senkyunolide I
Cat. No.：YN270479
| 产品名称: | Senkyunolide I |
| CAS No.: | 94596-28-8 |
| Chemical Name: | (3Z,6R,7R)-rel-3-butylidene-4,5,6,7-tetrahydro-6,7-dihydroxy-1(3H)-isobenzofuranone |
| Synonyms: | SEI, SENI |
| 分子量: | 224.25 |
| 分子式: | C₁₂H₁₆O₄ |
| SMILES: | O=C1O/C(C2=C1[C@H](O)[C@@H](O)CC2)=C\CCC |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | Senkyunolide I 可从Ligusticum chuanxiongHort 中分离得到，是一种抗偏头痛的化合物。Senkyunolide I 通过上调p-Erk1/2、 Nrf2/HO-1 以及抑制caspase 3 保护大鼠大脑免受局灶性脑缺血灌注损伤。 |
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Jiang, M., Zhou, M., Han, Y., et al.Identification of NF-κB Inhibitors in Xuebijing injection for sepsis treatment based on bioactivity-integrated UPLC-Q/TOFJ. Ethnaopharmacol.147(2),426-433(2013)
Huang, Y., Wu, Y., Yin, H., et al.Senkyunolide I: A review of its phytochemistry, pharmacology, pharmacokinetics, and drug-likenessMolecules28(8),3636(2023)
Wang, Y.-H.Effect and mechanism of senkyunolide I as an anti-migraine compound from Ligusticum chuanxiongJ. Pharm. Pharmacol.63(2),261-266(2010)
Xie, J., Zhao, Z.-Z., Li, P., et al.Senkyunolide I protects against sepsis-associated encephalopathy by attenuating sleep deprivation in a murine model of cecal ligation and punctureOxid. Med. Cell. Longev.,6647258(2021)
