Ivachtin
Cat. No.：YN270604
| 产品名称: | Ivachtin |
| CAS No.: | 745046-84-8 |
| Chemical Name: | 2-[2-(acetyloxy)ethyl]-4-methyl-8-(4-morpholinylsulfonyl)-1H-pyrrolo[3,4-c]quinoline-1,3(2H)-dione |
| Synonyms: | Caspase-3 Inhibitor VII |
| 分子量: | 447.46 |
| 分子式: | C₂₀H₂₁N₃O₇S |
| SMILES: | O=C1N(CCOC(C)=O)C(C2=C1C3=CC(S(=O)(N4CCOCC4)=O)=CC=C3N=C2C)=O |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | Ivachtin (Caspase-3 Inhibitor VII；化合物 7a) 是一种非肽，非竞争性和可逆的caspase-3抑制剂，IC50为 23 nM。Ivachtin 对其余的胱天蛋白酶具有适度的选择性。 |
| IC50和靶点: | [{name:"Caspase-3:23 nM (IC50)"}] |
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| Solvent & Solubility: |
Kravchenko, D.V., Kuzovkova, Y.A., Kysil, V.M., et al.Synthesis and structure-activity relationship of 4-substituted 2-(2-acetyloxyethyl)-8-(morpholine-4-sulfonyl)pyrrolo[3,4-c]quinoline-1,3-diones as potent caspase-3 inhibitorsJ. Med. Chem.48(11),3680-3683(2005)
