CCT241533
Cat. No.：YN290308
| 产品名称: | CCT241533 |
| CAS No.: | 1262849-73-9 |
| Chemical Name: | (3R,4S)-4-[[2-(5-Fluoro-2-hydroxyphenyl)-6,7-dimethoxy-4-quinazolinyl]amino]-α,α-dimethyl-3-pyrrolidinemethanol; |
| Synonyms: | CCT 241533;CCT-241533 |
| 分子量: | 442.48 |
| 分子式: | C₂₃H₂₇FN₄O₄ |
| SMILES: | COC1=C(OC)C=C(C(N[C@H]2[C@H](C(C)(C)O)CNC2)=NC(C3=C(O)C=CC(F)=C3)=N4)C4=C1 |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | CCT241533 是有效，选择性的CHK2抑制剂，IC50和Ki分别为 3 nM 和 1.16 nM。 |
| IC50和靶点: | [{name:"Chk2:3 nM (IC50)"},{name: "Chk1:245 nM (IC50)"},{name: "Chk2:1.16 nM (Ki)"}] |
| In Vitro: | |
| In Vivo: | |
| Clinical Trial: | |
| Solvent & Solubility: |
Caldwell, J. J., et al.: J. Med. Chem., 54, 580 (2011)
